Terlipressin acetate enim esophageal variceal sanguinem
Product Detail
| Nomen | N- (N- (n-glycylglycyl) Glycyl) -8-l-lysineVasopressin |
| Cas numerum | 14636-12-5 |
| MOLECULA | C52h74n16o15s2 |
| Pondus | 1227,37 |
| Einecs numerum | 238-680-8 |
| PRAETERITUS | 1824.0 ± 65.0 ° (Praedicta) |
| Densitas | 1.46 ± 0.1 G / CM3 (praedicta) |
| Conditions repono | Custodi in tenebris est, inerti atmosphaera, copia in freezer, sub -15 ° c. |
| Acetosum coefficientem | (Pka) 9.90 ± 0.15 (praedicta) |
Synonyma
[N-α-triglycyl-VIII-lysine] -vasopressin, CXXX: PN: Wo2010033207Seqid: 171Claedprotein; I-triglycyl, VIII-lysineVasopressin; Nα, glycyll-glycyll- glycyl- [VIII-lysine] -vasopressin; Nα, glycyl-glycyl-glycyl-lysine, Vasopressin; Nα-glycylglycylcylcylcyl, vasopressin; Nα-Gly-Gly-Gly-VIII-lys, Vasopressin; Terlipressin, Terlipressine, Terlipressina, Terlipressinum.
Descriptio
Terlipressin, quorum eget nomen triglycylysine Vasopressin est a novam syntheticam diu agens Vasopressin praeparatio. Est quaedam prodrug, qui inertes per se. Est egit per aminopeptidase in vivo ad tardius "release" et activae lysine Vasopressin post removere tres Glycyl residua in N-terminus. Ideo Terlipressin acts ut in alveus quod solvo lysine vasopressin ad stabilis rate.
Et pharmacological effectus de Terlipressin est ad contractus Splanchnic vascularium lenis musculus et redigendum Splanchnic sanguis fluxus (ut reducing sanguinem influunt in mesentery, lienis, utero sanguinem et Portal pressura. In alia manu, potest etiam ad redigendum plasma effectum Renin concentration, ita augendae renalis fluxus, melior renum et augendae urinam output in aegris cum Hepatoral syndrome. Terlipressin est currently solum medicamento, quod potest amplio superesset rate of aegris cum esophageal Varicesal Hemorrhage. Is est maxime in orci curatio de Variceal Hemorrhage. Praeterea, Terlipressin etiam feliciter usus est in iecoris et renibus. In generali, quod est verisimile ad ludere a utilis partes in coexisting refracting inpulsa et cardiopulmonary resuscitatio. Comparari vasopressin, quod habet diu manentem effectus, non faciam periculo inpedimenta, comprehendo fibrinolysis et gravi inpedimenta in cardiovascular ratio, et simplex utor (intravenous iniectio), quod est apta acuti et discrimine. Eripe et treatment of critico male aegris.
