Nomen | Vancomycin |
Cas numerum | 1404-90-6 |
MOLECULA | C66h75cl2n9o24 |
Pondus | 1449,25 |
Einecs numerum | 215-772-6 |
Densitas | 1.2882 (aspera estimate) |
Index refractive | 1.7350 (estimate) |
Conditions repono | Signatum siccis, 2-8 ° |
Vancomycin(baseand/orunspecifiedsalts);VANCOMYCIN;VancomycinBase;(3S,6R,7R,22R,23S,26S,36R,38aR)-3-(2-Amino-2-oxoethyl)-44-[[2-O-(3-amino-2, 3,6, trideoxy-III-c-y-l-hexopyranosyl-α-l-l-hexopyranosyl), -β-d-glucopyranosyl] 2,3,4,6,38,23,24,26,36,38,38,23,24,25,26,38,38a-VII-TetraDecahydro , 22,28,30,32-Pentahydroxy-VI - [[2r) -4 -4, MethchemicalBookyl, 2- (Methylamino) -1-Oxopentyl] -2,5,24,38,39, Pentaxo, 22h-8,21, 18,21, Pentaxo-22.-8,21, 18,21, Dietheno, XXIII, 36- (Iminhano) -13,16: 31,35-Dimetheno-1h, 16h- [1,6,9] OxadiazactionCoadecino [4,5-M] [10,2,16 [10,2.16] Benzoxadiazacycotetracosine-XXVI-carboxyllicacidacoclotetracosine
Vancomycin est glycopeptide antibiotic. Its mechanism of action is to bind with high affinity to the alanylalanine at the poly-terminal end of the precursor peptide of the sensitive bacterial cell wall, blocking the synthesis of the macromolecular peptidoglycan that constitutes the bacterial cell wall, resulting in Destruction of the cell wall kills bacteria. Vancomycin efficax gravis infectiones causatur per Gram-positivum Bacteria, praesertim causam a Methicillin repugnans Staphylococcus aureus, Staphylococcus et editococcus repugnant aliis antibiotics vel pauperes.
Est limitata ad systemica infectiones causatur a Methicillin repugnans Staphylococcus aureus (MRSA) et intestinorum infectiones et systemica infectiones per Clostridium difficile; Penicillin, allergic aegros non utor penicillins et cephalosporins in aegris cum gravibus Staphylococccccal infectio, aut eos cum gravibus Staphylococcccal infectio, qui non sunt ad Respondeo dicendum quod superius antibiotics, Vancomycin potest esse. Hoc productum est etiam propter curatio de Endocarditis et Corynebacterium (Diphtheria, sicut) endocarditis in populo allergic ad penicillin. Treatment of Staphylococcus-adductus arteriovenous shunt infectiones in hemodialysis aegros allergic ad penicillin et non-allergic ad penicillin.