103060-53-3 ad Morbi daptomycin
Product Detail
| Nomen | Daptomycin |
| Cas numerum | 103060-53-3 |
| MOLECULA | C72h1011n17o26 |
| Pondus | 1620.67 |
| Einecs numerum | 600-389-2 |
| Point liquescens | 202-204 ° C |
| PRAETERITUS | 2078,2 ± 65.0 ° C (praedicta) |
| Densitas | 1,45 ± 0.1 G / CM3 (praedicta) |
| Flash Point | LXXXVII ℃ |
| Conditions repono | Signatum in sicco, copia in freezer, sub -20 ° C |
| Solubility | Methanol: Solutum5MG / ml |
| Acetosum coefficientem | (Pka) 4.00 ± 0.10 (praedicta) |
| Forma | pulverem |
| Colo | hyalina ad deficiat flavo |
Synonyma
N-[N-(1-Oxodecyl)-L-Trp-D-Asn-L-Asp-]-cyclo[L-Thr*-Gly-L-Orn-L-Asp-D-Ala-L-Asp-Gly-D-Ser-[(3R)-3-methyl-L-Glu-]-4-(2-aminophenyl)-4-oxo-L-Abu-] ;N-[N-Decanoyl-L-Trp-D-Asn-L-Asp-]-cyclo[Thr*-Gly-L-Orn-L-Asp-D-Ala-L-Asp-Gly-D-Ser-[(3R)-3-methyl-L-Glu-]-3-(2-aminobenzoyl)-L-Ala-];N-(1-Oxod ecyl)-L-tryptophyl-D-asparaginyl-L-α-aspartyl-L-threonylglycyl-L-ornithinyl-L-α-aspartyl-D-alanyl-L-α-aspartylglycyl-D-seryl-(3R)-3-methyl-L-α- glutamyl, α, II-diamino-γ-oxo, benzenebutanoicacid (13-4) Lactone; daptomycine; Dapcin; dapcinreycin,> = XCIX, daptomycinreadymadesolody, VII (LY146032 =;
Descriptio
Et antibiotic daptomycin est cyclic lipopeptide antibiotic cum novum structuram extrahitur a fermentatione ius ex Stroture (S. Resosporatus), quae impeditur biosynthesis de bacterial cellula peptotoglycan per conturbant in murum in cellula in cell. Altering proprietatibus ex cytoplasmic membranam potest perturbare bacterialium membrana munus in multiple vias et cursim occidere gram-positivum bacteria. Praeter suam facultatem ad actum maxime amet pertinet gram, positivum Bacteria, daptomycin est magis pro methicillin, vancomycin, et linezolid in vitro. Hoc est potens actio, et haec res habet valde magna orci effectus in critico ill infici aegris. Eosinophilic Pneumonia est rara et valde gravis morbus cum symptoms inter febrem, tussis, brevitas spiritus et difficultate spiritus.
EXPLICIUM
Daptomycin habet bonum bacteriostatic actio contra variis antibiotic, repugnant bacteria, ut microform = 0.06-0.5 μg / ml for Methicillin repugnans Staphylococcus aureus (MRSA (MRSA). Microform = 0.0625 ~ 1μg / ml pro Bacteria, mic = 0,5μg ~ / ML pro oxacillin-repugnant Staphylococcus, microform = 0.5 ~ 1μg / m m micr Enterococcus repugnant ad Glycopeptide antibiotics est I ~ 2μg / ml.
