Sildenafil citrate agitur erectile dysfunction 171599-83-0

Pharmacological actio
Selferenafil citrate est selectivam V-phosphodiesterase inhibitor quod enhances nitric cadmiae, dependens, cyclic guanosine monophosphate-mediated pulmonalis vasodilation per inhibendo de naufragii Cyclic Guanosine Monophosphate. Insuper ad directum expansion pulmonalis sanguine vasa, potest etiam ne vel vicissim vascularium molestie.

Medicinales proprietatibus et applications
Sildenafil citrate, commercia nomen viagre, communiter ut viagra, est Cyclic Guanosine Monophosphate (CGMP) -specific phosphodiesterase Type V (Pde5) inhibitor quod potest augendae erectionem post oralis administratione. Sildenafil citrate potest augendae effectum nitric cadmiae (non) per inhibentes genus V phosphodiesterase quod decomposes cyclic guanosine monophodiesterase (CGMP) in Corpus Cavmp. Ad augmentum campester of CGMP in Corpus cavernosum, relaxat lenis musculus in corpus capavernosum, crescere influxum sanguinis, protrahendum penis erectione et crescere firmitatem. Nam impotentia aegris cum erectile distemperantia. Adultis tolle L mg viva per tempus, usque ad I tempus dies, et uti ut opus circa I hora ante sexualem. Maxime quantum 0.1G per tempus.

In Vivo Studies
In anesthetized canes, sildenafil citrate augendae poenile erectile function sub intrapelvicum nervi excitanda per mensuræ Intracavernous pressura. Sildenafil citrate insigniter reversed imminuta carbamoylcholine, excitatur relaxationem et inhibuit superexide formatio in cavernosal TEXTUS hypercholesterolemic cuniculorum. In sprague, Dawley mures, Sildenafil improves erectile munus in tempore-dose-dependens modo, cum maxima recuperatio occurrenti die XXVIII ad dose of XX mg / kg per diem. In Sprague, Dawley mures, administrationem Sildenafil consecrata lenis musculus collagen Ratio conservationem et conservationem CD31 et Enos expressio. In sprague, Dawley mures, Sildenafil significantly reducitur Apoptotic index et auctus phosphorylation of akt et Enos comparari cum imperium coetus.