Tianeptine sodium pro depressive episodes

Usuria

Eam maxime acts in V-HT system, sine excitement, sedation, anti-acetylcholine et cardioxicity. Quia tristitia.

Pharmacological effectus

I. De antidepressant mechanism of is uber est aliud ex eo traditional TCA. Potest crescere uptake de V-HT in Synaptic scampiam, sed habet debilior effectus in reuptake de V-HT et na. Sit autem effectus enhancing V-ht neuronal tradenda. Non habet affinitatem ad M Receptatores, H1, α1 et α2-na receptores.
II. Et antidepressant efficaciam huius productum est similis, quod de TCA et ad salutem et tolerability sunt melius quam TCA (Tricyclic antidepressants). Et efficaciam huius productum est similis, ut SSRI fluoxetine.
III. Animal medicamento experimenta ostensum est quod potest: proventus spontanea operatio pyramidalis cellulis in hippocampus et accelerate recuperatio ejus munus post inhibitionis; Auget reabsorption de V-hydroxytryptamine per neurons in cerebri cortex et hippocampus.

Toxicology Studies

- acutus, subacute et longa-term toxicity probat: Nulla mutationes in biology, iecoris munus, pathologicas anatome.
- generatiua toxicity et Teratogenicity Test: Tianeptine non habet effectum in generatiua facultatem tractata parentes et in foetum et proles.
- Mutagenicity Test: Tianeptine habet mutagenic effectus.