Tianeptine ad V-HT system, sedation, anti-acetylcholine et cardioxicity ad demissionem
Product Detail
| Nomen | Tianeptine |
| Cas numerum | 1224690-84-9 |
| MOLECULA | C21h27cln2o8s2 |
| Pondus | 535,02 |
| Point liquescens | 129-131 ° C |
| PRAETERITUS | 660 MMCHG 609.2ºC |
| Pudicitia | XCIX% |
| Repono | Signatum in sicco, locus temperatus |
| Forma | Pulverem |
| Colo | Alba |
| Stipare | PE lapides sacculi + Aluminium |
Synonyma
THM;Tianeptinehemisulfatemonohydrate(THM);Tianeptinehemisulfatehydrate;TongKangzuo;tianeptinesulfate;Tianeptinesulphatepowder;TianeptineSemisulfateMonohydrate;TTianeptinesulfateianeptinesulfate;tianeptinesodiumTianeptinesulfate;Tineptinesulphatepowder/Tianeptinsulfate
Pharmacological effectus
Pharmacological effectus
I. De antidepressant mechanism of is uber est aliud ex eo traditional TCA. Potest crescere uptake de V-HT in Synaptic scampiam, sed habet debilior effectus in reuptake de V-HT et na. Sit autem effectus enhancing V-ht neuronal tradenda. Non habet affinitatem ad M Receptatores, H1, α1 et α2-na receptores.
II. Et antidepressant efficaciam huius productum est similis, quod de TCA et ad salutem et tolerability sunt melius quam TCA (Tricyclic antidepressants). Et efficaciam huius productum est similis, ut SSRI fluoxetine.
III. Animal medicamento experimenta ostensum est quod potest: proventus spontanea operatio pyramidalis cellulis in hippocampus et accelerate recuperatio ejus munus post inhibitionis; Auget reabsorption de V-hydroxytryptamine per neurons in cerebri cortex et hippocampus.
Toxicology Research
- acutus, subacute et longa-term toxicity probat: Nulla mutationes in biology, iecoris munus, pathologicas anatome.
- generatiua toxicity et Teratogenicity Test: Tianeptine non habet effectum in generatiua facultatem tractata parentes et in foetum et proles.
- Mutagenicity Test: Tianeptine habet mutagenic effectus.
Parte effectus
- epigastricus dolor, abdominis dolor, arida oris, anorexia, nausea, vomitus, constipation, flatibus;
- Insomnia, somno, somnia, infirmitate;
- Tachycardia, Extrasoles, Precordialem dolorem;
- vertigine, capitis, deficientes, tremores, rutilant vultus;
- brevitas spiritus, animi obstructio in faucibus;
- Myalgia, retro dolor, etc.
